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Table 2 (

Continued

)

Study ID (year), country,

design, recruitment period

PROM tool used

Interventions

N

Age: mean (SD),

median [range]

{95% CI}

FU (mo):

mean (SD),

median [range]

T stage

Gleason score:

n

or mean (SD)

PSA:

n

mean (SD),

median [range]

Comorbidity

EPIC

EBRT

52 68 [48–77]

T2a: 43 (83%)

<

7: 39 (75%)

8 [2.5–24]

Hypertension: 11 (21%)

Coronary heart disease: 13 (25%)

Diabetes: 7 (14%)

COPD: 6 (12)

Punnen

(2014)

e [2

5]

, U

SA,

prospective, 1995–2011

NS radical

prostatectomy

1139 60.0 (6.8)

73 [51–100]

NR

NR

NR

None: 228 (20%)

1: 384 (34%)

2: 309 (28%)

3: 201 (18%)

Non-NS radical

prostatectomy

860 62.9 (6.6)

76 [51–103]

None: 148 (18%)

1: 249 (29%)

2: 226 (27)

3: 224 (26)

Brachytherapy

684 68.3 (7.2)

83 [52–104]

None: 61 (9%)

1: 168 (25%)

2: 202 (31%)

3: 233 (35%)

UCLA-PCI

EBRT

386 71.3 (6.2)

71 [48–100]

None: 31 (8%)

1: 85 (22%)

2: 110 (29%)

3: 155 (41%)

Resnick

(2013)

[26] /

Potosky

(2004)

[23] /

Potosky

(2000)

[24] ,

USA, prospective,

1994–1995

Radical

prostatectomy

1164 64 [59–68]

180

T1: 377 (32.4%)

T1/T2: 279 (24.0%)

T2: 508 (43.6%)

2–4: 743 (64%)

5–7: 216 (18%)

8–10: 73 (7%)

Unknown:

132 (11%)

<

4: 122 (10%)

4–10: 703 (61%)

>

10: 339 (29%)

Number of coexisting illnesses

0: 513

1: 368

2: 179

3: 104

PCOS questionnaire

EBRT

491 69 [64–71]

T1: 150 (30.6%)

T1/T2: 118 (24.1%)

T2: 222 (45.3)

2–4: 292 (59%)

5–7: 110 (22%)

8–10: 46 (10%)

Unknown:

43 (9%)

<

4: 43 (9%)

4–10: 252 (56%)

>

10: 196 (35%)

Number of coexisting illnesses

0: 159

1: 160

2: 93

3: 79

Sanda

(2008)

[27] , U

SA,

prospective, 2003–2006

Radical

prostatectomy

603 59 [38–79]

30

T1: 436 (72%)

T2: 167 (28%)

<

7: 371 (62%)

7: 207 (34%)

>

7: 25 (4%)

<

4: 126 (21%)

4–10: 399 (66%)

>

10: 78 (13%)

Mean number of coexisting illnesses

0.9 (1.1)

EPIC

EBRT

292 69 [45–84]

T1: 202 (69%)

T2: 90 (31%)

<

7: 129 (44%)

7: 123 (42%)

>

7: 40 (14%)

<

4: 46 (16%)

4–10: 177 (61%)

>

10: 69 (24%)

Mean number of coexisting illnesses

1.5 (1.2)

Brachytherapy

306 65 [44–84]

T1: 254 (83%)

T2: 51 (17%)

<

7: 227 (74%)

7: 76 (25%)

>

7: 2 (1%)

<

4: 67 (22%)

4–10: 217 (71%)

>

10: 21 (7%)

Mean number of coexisting illnesses

1.3 (1.1)

Schapira

(2001)

f [2

8]

,

USA, prospective, NR

Radical

prostatectomy

42 64 [58–68]

12

T1: 55%

T2: 45%

2–4: 30%

5–6: 49%

7: 19%

8–10: 3%

7.6 [4.9–11.1]

Charlson Comorbidity Index

0.57 (0.99)

UCLA-PCI

EBRT

51 73 [68–75]

T1: 43%

T2: 57%

2–4: 16%

5–6: 51%

7: 29%

8–10: 4%

7.1 [4.9–12.3]

Charlson Comorbidity Index

2.0 (2.1)

E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 8 6 9 – 8 8 5

876