

Table 2 (
Continued
)
Study ID (year), country,
design, recruitment period
PROM tool used
Interventions
N
Age: mean (SD),
median [range]
{95% CI}
FU (mo):
mean (SD),
median [range]
T stage
Gleason score:
n
or mean (SD)
PSA:
n
mean (SD),
median [range]
Comorbidity
EPIC
EBRT
52 68 [48–77]
T2a: 43 (83%)
<
7: 39 (75%)
8 [2.5–24]
Hypertension: 11 (21%)
Coronary heart disease: 13 (25%)
Diabetes: 7 (14%)
COPD: 6 (12)
Punnen
(2014)
e [25]
, USA,
prospective, 1995–2011
NS radical
prostatectomy
1139 60.0 (6.8)
73 [51–100]
NR
NR
NR
None: 228 (20%)
1: 384 (34%)
2: 309 (28%)
3: 201 (18%)
Non-NS radical
prostatectomy
860 62.9 (6.6)
76 [51–103]
None: 148 (18%)
1: 249 (29%)
2: 226 (27)
3: 224 (26)
Brachytherapy
684 68.3 (7.2)
83 [52–104]
None: 61 (9%)
1: 168 (25%)
2: 202 (31%)
3: 233 (35%)
UCLA-PCI
EBRT
386 71.3 (6.2)
71 [48–100]
None: 31 (8%)
1: 85 (22%)
2: 110 (29%)
3: 155 (41%)
Resnick
(2013)
[26] /Potosky
(2004)
[23] /Potosky
(2000)
[24] ,USA, prospective,
1994–1995
Radical
prostatectomy
1164 64 [59–68]
180
T1: 377 (32.4%)
T1/T2: 279 (24.0%)
T2: 508 (43.6%)
2–4: 743 (64%)
5–7: 216 (18%)
8–10: 73 (7%)
Unknown:
132 (11%)
<
4: 122 (10%)
4–10: 703 (61%)
>
10: 339 (29%)
Number of coexisting illnesses
0: 513
1: 368
2: 179
3: 104
PCOS questionnaire
EBRT
491 69 [64–71]
T1: 150 (30.6%)
T1/T2: 118 (24.1%)
T2: 222 (45.3)
2–4: 292 (59%)
5–7: 110 (22%)
8–10: 46 (10%)
Unknown:
43 (9%)
<
4: 43 (9%)
4–10: 252 (56%)
>
10: 196 (35%)
Number of coexisting illnesses
0: 159
1: 160
2: 93
3: 79
Sanda
(2008)
[27] , USA,
prospective, 2003–2006
Radical
prostatectomy
603 59 [38–79]
30
T1: 436 (72%)
T2: 167 (28%)
<
7: 371 (62%)
7: 207 (34%)
>
7: 25 (4%)
<
4: 126 (21%)
4–10: 399 (66%)
>
10: 78 (13%)
Mean number of coexisting illnesses
0.9 (1.1)
EPIC
EBRT
292 69 [45–84]
T1: 202 (69%)
T2: 90 (31%)
<
7: 129 (44%)
7: 123 (42%)
>
7: 40 (14%)
<
4: 46 (16%)
4–10: 177 (61%)
>
10: 69 (24%)
Mean number of coexisting illnesses
1.5 (1.2)
Brachytherapy
306 65 [44–84]
T1: 254 (83%)
T2: 51 (17%)
<
7: 227 (74%)
7: 76 (25%)
>
7: 2 (1%)
<
4: 67 (22%)
4–10: 217 (71%)
>
10: 21 (7%)
Mean number of coexisting illnesses
1.3 (1.1)
Schapira
(2001)
f [28]
,USA, prospective, NR
Radical
prostatectomy
42 64 [58–68]
12
T1: 55%
T2: 45%
2–4: 30%
5–6: 49%
7: 19%
8–10: 3%
7.6 [4.9–11.1]
Charlson Comorbidity Index
0.57 (0.99)
UCLA-PCI
EBRT
51 73 [68–75]
T1: 43%
T2: 57%
2–4: 16%
5–6: 51%
7: 29%
8–10: 4%
7.1 [4.9–12.3]
Charlson Comorbidity Index
2.0 (2.1)
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 8 6 9 – 8 8 5
876