EURURO Vol. 72 No. 6

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EPIC

IMRT

160 69 (7.4)

T1: 128 (80%)

T2:32 (20%)

2–6: 99 (62%)

7: 60 (38%)

8–10: 1 (0.6%)

N/A: 0

5.8 (4.2)

SBRT

381 70 (7.4)

T1:289 (76%)

T2:92 (24%)

2–6: 211 (55%)

7: 164 (43%)

8–10: 5 (1.3%)

N/A: 1 (0.26%)

6.1 (3.9)

Jeldres

(2015)

[17]

SA,

prospective, 2007

Active surveillance

77 65 (8.1)

27 (17)

T1a–T1c: 50 (65%)

T2a: 27 (35%)

NR but inclusion

criteria state that

biopsy Gleason

score: 6

4.0 (1.9)

0: 17

1: 21

2: 39

EPIC

Radical

prostatectomy

228 58 (7.4)

36 (17)

T1a–T1c: 161 (71%)

T2a: 67 (29%)

4.2 (1.9)

0: 56

1: 86

2: 86

Kobuke

(2009)

[18]

Japan, prospective,

2004–2005

Radical

prostatectomy

37 67 [54–75]

12

T1: 19 (51%)

T2: 18 (49%)

6: 14 (38%)

7: 18 (49%)

8–9: 5 (13%)

8.31 [1.796–27.44]

NR

UCLA-PCI

Brachytherapy

36 67 [53–76]

T1: 17 (47%)

T2: 19 (53%)

6: 21 (58%)

7: 7 (20%)

8–9: 8 (22%)

7.73 [1.13–74]

Malcolm

(2010)

USA, prospective,

2000–2008

Open radical

prostatectomy

135 59 (7)

36

T1c or less: 112 (83%)

T2a: 17 (13%)

T2b+: 6 (4%)

Unknown: 0

6: 93 (69%)

7: 34 (25%)

8: 8 (6%)

5.7 [4.7–7.3]

NR

UCLA-PCI

Robotic radical

prostatectomy

447 59 (6)

T1c or less: 340 (76%)

T2a: 68 (15%)

T2b+: 32 (7%)

Unknown: 7 (2%)

6: 269 (60%)

7: 154 (34%)

8: 24 (5%)

5.2 [3.9–6.8]

Brachytherapy

122 66 (7)

T1c or less: 98 (80%)

T2a: 16 (13%)

T2b+: 3 (2%)

Unknown: 5 (4%)

6: 88 (72%)

7: 28 (23%)

8: 6 (5%)

6.0 [4.5–8.2]

Namiki

(2006)

[20]

Japan, prospective,

2004–2005

Radical

prostatectomy

67 64.3 (6.5)

12

T1: 50 (75%)

T2: 17 (25%)

6: 12 (18%)

7: 55 (82%)

8.8 (6.8)

NR

UCLA-PCI

Brachytherapy

70 67.0 (6.4)

T1: 56 (80%)

T2: 14 (20%)

6: 47 (67%)

7: 23 (33%)

7.0 (3.4)

Pardo

(2010)

[21]

ain,

prospective, 2003–2005

Radical

prostatectomy

123 64.2 (5.5)

36

T1: 82 (67%)

T2: 41 (33%)

Unknown: 0

6.9 (6.4)

8.0 (3.3)

Number of chronic conditions

2.33 (1.5)

EPIC

EBRT

127 69.5 (5.4)

T1: 73 (57%)

T2: 53 (42%)

Unknown: 1 (1%)

5.9 (1.0)

8.2 (4.7)

Number of chronic conditions

2.5 (1.8)

Brachytherapy

185 66.0 (7.0)

T1: 152 (82%)

T2: 33 (18%)

Unknown: 0

5.9 (5.3)

6.8 (2.1)

Number of chronic conditions

2.3 (1.6)

Pinkawa

(2009)

[22]

Germany, prospective,

2003–2006

Brachytherapy

52 68 [51–77]

16

T2a: 51 (98%)

<

7: 50 (96%)

7 [1.5–14]

Hypertension: 11 (21%)

Coronary heart disease: 6 (12%)

Diabetes: 6 (12%)

COPD: 4 (8%)

E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 8 6 9 – 8 8 5

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