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4.

Discussion

In this study we provide multi-center outcome data for

patients undergoing RPL and RNL for the management of

renal stones. We found that the complete SFR after a single

robotic procedure was 96%. Our overall complication rate

was 18.5%, with only 7.4% of patients having a Clavien

3 complication. None of the patients underwent a blood

transfusion or developed sepsis after RPL or RNL. The

procedures were done without the need for renal ischemia,

and in patients undergoing RPL, there was no transgression

of the renal parenchyma.

Robotic stone surgery has previously been shown to be a

reasonable approach for removing large staghorn stones

[3,13]

. Badani and colleagues

[13]

described robotic

extended pyelolithotomy in 13 patients, in which staghorn

or partial staghorn stones were treated. All but one patient

with a complete staghorn stone had removal of the entire

stone specimen, providing a SFR of 92%. Hemal et al

[14]

performed eight cases of robotic-assisted laparoscopic

surgery for primary stone removal, with a SFR of 93.2%.

Ghani et al

[3]

presented results on three patients with

complex staghorn stones who underwent robotic ana-

trophic nephrolithotomy with cold ischemia of the kidney.

In this select group, however, two of the three patients had

RFs following the procedure.

Table 3

provides a summary of

all studies to date assessing robot-assisted and laparoscopic

approaches to pyelolithotomy and renal stone removal

[11,13,15–25] .

Our study is the largest series to date

evaluating the safety and efficacy of a robotic approach to

treat renal stones.

The advantage of RPL or RNL is that it results in complete

stone removal in a minimally invasive fashion, reducing the

risk of RFs. Fragments following PCNL have the potential for

long-term morbidity due to need for surgical retreatment.

Raman et al

[7]

evaluated 42 patients with RFs after PCNL

confirmed on CT, and found that 43% of patients experi-

enced a stone related event at a median of 32 mo, and 61% of

these required a repeat surgical procedure. On multivari-

able analysis, RF size

>

2 mm was the only independent

predictor associated with a repeat stone event. More

recently, Portis and colleagues

[8]

assessed long-term

outcomes in 129 patients undergoing PCNL with a mean

follow-up of 5.4 yr. Patients who were completely stone-

free had a lower rate of a repeat procedure (4%), whereas

those with RF

>

2 mm or even

<

2 mm, had repeat procedure

rates of 30% and 33%, respectively. This implies that even

small RFs

<

2 mm may have significant consequences, and

that a zero-fragment outcome has the most desirable result.

Robotic minimally invasive surgery offers the possibility of

a one-stop solution for the removal of large renal stones,

and permits a

zero-fragment nephrolithotomy

, that is zero

fragmentation with the aim of intact complete stone

removal. The appeal of a single definitive procedure is

strong and robotic pyelolithotomymay be the best option in

some cases

[15]

. There are select indications when

nephrolithotomy is feasible, such as when the overlying

parenchyma for a peripherally located stone is thin or the

stone is in a calyceal diverticulum.

RPL allows removal of stones through an incision of the

renal pelvis without transgressing the parenchyma, which

is a potential cause for bleeding and nephron loss. A select

group of patients that one could consider RPL include

patients with unfavorable anatomy,

anticoagulated

patients, concomitant ureteropelvic junction obstruction,

ectopic kidney, and failed PCNL

[26]

. We acknowledge that

robotic surgery should not be the initial treatment choice

for most patients with renal stones, and that endourologic

management is the standard of care. A further point

regarding RPL is that in some patients, dissection of the

renal pelvis can be challenging as the pelvis may be

inflamed with adherent fat, making demarcation of planes

difficult with bleeding encountered.

RNL may be the better option in cases where access to

the collecting system through the renal pelvis is restricted.

The robotic ultrasound probe is used to both locate the

stone and plan the incision, which is best if performed in the

thinnest part of the parenchyma. If done appropriately,

bleeding is minimal and clamping not necessary. Further, as

we have shown in the accompanying video, RNL is able to

successfully treat calyceal diverticular stones, especially

posterior lying stones via a retroperitoneal approach. One

note on technique here should be addressed; if the

diverticulum orifice is not well localized, or hydrocalyx is

suggested as a differential diagnosis, we recommend

ablation in order to avoid a urine leak from an unablated

hydrocalyx

[27] .

The advantages of a retroperitoneal

approach are that the bowel and peritoneal cavity are not

transgressed, allowing quicker return of bowel function as

well as a more rapid dissection to the hilum

[28]

. Dis-

advantages to this approach are that it requires greater

expertise to develop the space, particularly in obese

patients, as well as longer preconsole operative times for

access and port placement as noted in our series.

Some shortcomings of robotic renal stone surgery

compared with PCNL need to be noted. First, PCNL should

be considered the least invasive approach, especially in a

single access approach as there is only one skin incision.

However, with complex stones, multiple tracts for PCNL

may be needed which increases the number of incisions.

[8_TD$DIFF]

Second, flexible nephroscopy is more easily performed

during PCNL than via a laparoscopic port.

[9_TD$DIFF]

Third, in patients

who have soft stones, PCNL with an energy device

incorporating suction may lead to easier stone clearance.

RPL and RNL are more suited for hard stones that can be

grasped and removed intact.

[10_TD$DIFF]

Finally, data is not clear about

the costs of robotic surgery for renal stones. A recent study

by Hyams and Shah

[29]

calculated PCNL to cost $19 845 in

the USA. Using robotic partial nephrectomy as a surrogate

for the cost of RPL or RNL, a study by Mir and colleagues

[30]

estimates the cost of robotic partial nephrectomy to be $11

962. Charges and ancillary equipment used may vary

between institutions, and comparing costs is difficult.

Limitations of our study include absence of postoperative

imaging in four patients. However, these patients were

assessed intraoperatively under robotic vision, and were

patients who had solitary stones removed intact. Of

23 patients undergoing postoperative imaging, CT was used

E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 1 0 1 4 – 1 0 2 1

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